A dismembered body is found in Kill Buck Wildlife area in Snug Harbor, Ohio, and the discovery of two more victims within a twelve mile radius suggests a sadistic killer's return. Homicide Detective Rachel Hood, a psychic empath, joins forces with psychic FBI Agent Nick Draven to hunt for a killer who harvests kidneys from his victims' corpses. But, why strike twenty years later? They draw a parallel between his first crime and the recent murders. His first victim was murdered in 1991 during the rare occurrence of the super harvest moon, an event that will happen this year and fuel his blood lust to kill again.

Time is not on their side. Hood and Draven have five days to find the killer before the next full moon rises and another teenage girl is found murdered and missing her kidneys.

Drawn into a hunt for a serial killer, more deranged and dangerous than any other she's tracked and captured before, Hood finds herself unable to control her psychic empathy, and Draven must work fast to help her catch this human hunter before she becomes his next casualty.